Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity
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چکیده
منابع مشابه
Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity
OBJECTIVE Antinuclear antibodies (ANAs) are detected in ∼18% of females, yet autoimmune disease develops in only 5-8%. Immunologic differences between ANA-positive healthy individuals and patients with systemic lupus erythematosus (SLE) may elucidate the regulatory mechanisms by which ANA-positive individuals avoid transition to clinical autoimmune disease. METHODS Healthy individuals (n = 79...
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Article history: Received 9 May 2016 Accepted 9 May 2016 Available online 13 May 2016 (insulinemia N24.9 mIU/L, odds ratio [OR] 12.17%, p = 0.011), high tryglycerides (N2.85 mM, OR 4.18, p = 0.038) and lipodystorphy (OR 4.87, p= 0.015). Several studies have demonstrated that markers of inflammation, including levels of TNFR-I and II, are predictive ofmorbidity and mortality in persons infected ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatology
سال: 2016
ISSN: 2326-5191,2326-5205
DOI: 10.1002/art.39706